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Product Description
Guyton and Hall Textbook of Medical Physiology, 15th Edition, is Elsevier’s hardcover physiology textbook, the most widely used physiology text for medical students worldwide.
Guyton and Hall explains how the body works as an integrated system, with homeostasis as the organizing idea. The book’s two-font layout is its signature: fundamentals are set in larger type so you can skim the essentials fast, and supporting detail – clinical examples, pathophysiology, mechanisms – sits in smaller type highlighted in pale blue for when you want depth. Chapters are short and written in a plain, readable voice, which is why generations of students have found it easier to learn from than its competitors.
What’s included
- 15th Edition, hardcover, published by Elsevier
- ISBN-13: 9780443111013
- Full coverage of cell, membrane, cardiovascular, renal, respiratory, gastrointestinal, endocrine, reproductive, and nervous system physiology
- New content on physiology and the gut microbiome and on clinically important sex differences in lab values
- More than 1,200 full-color drawings and diagrams
- Two-font format separating core concepts from supporting detail
- Online access to heart sounds, animations, and self-assessment questions through the publisher
Who it’s for
First- and second-year MD and DO students in systems-based curricula, physician assistant and advanced practice nursing students who take graduate physiology, dental and pharmacy students, and undergraduates in rigorous pre-med physiology courses. Residents and USMLE Step 1 candidates go back to it when a review book’s one-line explanation is not enough.
Why this edition
The 15th edition keeps the format students know and updates the science, notably the microbiome content and sex-based differences in reference values that now matter for clinical decision making. If your school lists Guyton and Hall as the course text, the 15th is the current edition and the one your instructors will reference.
Frequently asked questions
Is the 15th edition the latest Guyton and Hall?
Yes. The 15th edition is the current edition of Guyton and Hall Textbook of Medical Physiology.
Is Guyton and Hall good for USMLE Step 1 preparation?
It is a full textbook rather than a review book, so students use it to build understanding during coursework and then review with a dedicated Step 1 resource.
Does the hardcover include online access?
Elsevier provides online resources with new copies of the book; access terms are set by the publisher and printed inside the book.
Details
| Title | Guyton and Hall Textbook of Medical Physiology |
|---|---|
| Edition | 15th Edition |
| Format | Hardcover |
| Publisher | Elsevier |
| ISBN-13 | 9780443111013 |
| Condition | New |

